About the 2025 World Sepsis Day
Sepsis remains one of the leading causes of death, disability, and healthcare costs worldwide. Affecting 48.9 million people annually and responsible for nearly 1 in 5 global deaths, Sepsis is a largely invisible global health emergency. It disproportionately affects vulnerable populations, including 20 million children, 26 million women, older adults, and immunocompromised individuals.
According to the latest estimates from the Institute of Health Metrics and Evaluation (IHME) and the University of Oxford, in 2021 alone, Sepsis was linked to 21 million deaths (as an immediate and intermediate cause), including 4 million deaths associated with or attributable to antimicrobial resistance (AMR).
Since 2012, over 54,000 stakeholders from 170 countries - including policy makers, national health authorities, healthcare providers, researchers, innovators, advocates, Sepsis survivors, families affected by this devastating medical emergency, and medical students – mark the World Sepsis Day (WSD) on September 13.
World Sepsis Day was initiated by the Global Sepsis Alliance (GSA) – the largest professional and advocacy network in the fight against Sepsis. WSD campaign events are held by GSA members and partners across Africa, Asia-Pacific, Europe, Eastern Mediterranean, Latin America and the Caribbean, and North America. These campaigns include scientific conferences, training sessions, media outreach, and the launch of national, regional, or global initiatives on Sepsis literacy or advocacy.
World Sepsis Day campaigns were convened under the Patronage of Dr. Tedros Adhanom Ghebreyesus, WHO Director-General, and the Federal Health Minister of Germany in 2023 and 2024.
2024 World Sepsis Day was marked by the historic launch of the 2030 Global Agenda for Sepsis at the German Parliament, the first multi-year strategy to prevent 12 million new Sepsis cases and save 2 million lives over the next 5 years.
The 2025 World Sepsis Day aims to further this momentum by emphasizing public awareness, political leadership, and strategic investments under the theme “5 Facts x 5 Actions” — to catalyze multisectoral engagement and prioritize Sepsis in global health planning.